Research

Our group have presented and published the following;

Brain natriuretic peptide and NT-proBNP levels reflect pulmonary artery systolic pressure in trekkers at high altitude.  Woods DR, Mellor A, Begley J, Stacey M, O’Hara J, Hawkins A, Yarker J, Foxen S, Smith C, BoosC. Physiol Res. 2013 Jul 17.

Cardiac biomarkers and high altitude pulmonary edema. Boos CJ, Holdsworth DA, Woods DR, Green K, Naylor J, Mellor A.   Int J Cardiol. 2013 Aug 10;167(3):e65-6. doi: 10.1016/j.ijcard.2013.03.119. Epub 2013 Apr 28.

The cortisol response to hypobaric hypoxia at rest and post-exercise.   Woods DR, Davison A, Stacey M, Smith C, Hooper T, Neely D, Turner S, Peaston R, Mellor A.   Horm Metab Res. 2012 Apr;44(4):302-5. doi: 10.1055/s-0032-1304322. Epub 2012 Feb 24. 

 The effects of prolonged acute hypobaric hypoxia on novel measures of biventricular performance.  Boos CJ, Hodkinson PD, Mellor A, Green NP, Bradley D, Greaves K, Woods DR.  Echocardiography. 2013 May;30(5):534-41. doi: 10.1111/echo.12088. Epub 2013 Jan 11.
The effects of acute hypobaric hypoxia on arterial stiffness and endothelial function and its relationship to changes in pulmonary artery pressure and left ventricular diastolic function.  Boos CJ, Hodkinson P, Mellor A, Green NP, Woods DR.   High Alt Med Biol. 2012 Jun;13(2):105-11. doi: 10.1089/ham.2012.1009.
Severe acute mountain sickness, brain natriuretic peptide and NT-proBNP in humans.  Woods DR, Begley J, Stacey M, Smith C, Boos CJ, Hooper T, Hawkins A, Hodkinson P, Green N,Mellor A.   Acta Physiol (Oxf). 2012 Jul;205(3):349-55. doi: 10.1111/j.1748-1716.2012.02407.x. Epub 2012 Jan 25.

Woods D, Hooper T, Hodkinson P, Ball S, Wakeford R, Peaston B, Bairsto C, Green N, Mellor A. Effects of altitude exposure on brain natriuretic peptide in humans. European Journal of Applied Physiology 2011, 10.1007/s00421-011-1881-8

Woods D, Hooper T, Mellor A, Hodkinson P, Wakeford R, Peaston B, Ball S, Green N. Brain natriuretic peptide and acute hypobaric hypoxia in humans. The Journal of Physiological Sciences 2011, 61, 217-220.

Brain natriuretic peptide shows no response to acute hypobaric hypoxia in humans. David Woods, Tim Hooper, Adrian Mellor, Pete Hodkinson, Rob Wakeford, Bob Peaston, Steve Ball, Nic Green. Presented at the British Endocrine Society, Manchester UK 15-18 March 2010. Published: Endocrine Abstracts (2010) 21 P159

Mellor A, O’Hara J.   First Aid, Travel and Acclimatisation. In: Cook Bunting O’Hara (Eds). Mountaineering; Preparation and Training. Human Kinetics, 2010.

TJ Hooper, DZH Levett, AJ Mellor, MPW Grocott.    Resting and exercising cardiorespiratory variables and acute mountain sickness.   Journal Royal Naval Medical Service 2010

Mountains, Medicine and Managers, presentation at Royal Society of Medicine, London, Mar 2008

In addition experience gained on DMS medical scientific expeditions enabled the publication of a special edition of the JRAMC published in March  2011 (vol 157(1)).  Contributing authors included previous expedition members and national experts.